I'm installing a ham radio transceiver into my car, which draws up to 25 amps and can't be used with the 12V socket. Instead, I'm following this and this and similar guides, which recommend running a dedicated pair of 10 AWG wires to the positive battery lead and engine ground point. (They recommend not using a chassis ground because of the RF interference it introduces.)
Most of these ham guides recommend using fuses on both wires in the engine compartment as well as the radio end. However, do I really want the ground wire to be fused? If something bad happens, don't I want an unimpeded path to ground? Is there a failure mode where having a fuse on the ground wire is beneficial?
This question is about ham radios, but I suspect it applies to standard car audio as well.