I had some severe vibration, which started suddenly, in my Transit camper. As soon a safe I pulled over and checked the tyres and wheel nuts. No obvious damage but I didn't spend long because I was causing an obstruction. There was no smell of hot brakes or rubber. The rev counter was fluctuating but I reckoned it to be wheel-related rather than engine-related because the feel changed with speed but not revs (including coasting in neutral).
I drove on slowly looking for a better place to stop and the vibration went away after a few minutes, before I could find somewhere to get right off the busy country road. The handling seemed normal once the vibration stopped - I'm sure I wasn't running on a flat.
About 10-20 minutes (<15 miles) later, BANG went the back left tyre. Luckily I could pull off the road to change the wheel (a rather laborious task on a Mk6 Transit made more so by a rusty spare-wheel mechanism) and all is well. The tread of the tyre was lying in the road about where I was when it went bang.
I'm trying to get my head round what happened. Clearly the vibration (which was enough to loosen screws in the living area above) was coming from the wheel, but why did the vibration go away with the tyre still inflated? Given that I pulled off the road when it started vibrating and the wheel looked OK, what warning signs did I miss? Would it have been worth moving the van a few feet and inspecting all the wheels again? I was the only adult present so couldn't watch the wheels and roll along.