I noticed this article about [Good to Run A/C in winter]. Well, it used to be true that it was a good idea to run your AC every few weeks in the winter, just to keep the seals in good condition. I suspect this may no longer be needed due to improvement in materials, but I'd like to hear from someone who knows.
Nowadays the compressor cycles on and off even when the A/C is not in use. This occurs all year long to maintain system pressure and maintain the integrity of the seals. In the old days and I am old enough those days. Because of the fact that the A/C wasn't periodically run the refrigerant and the oil would pool in bottom of the condenser core. The seals would dry out and let moisture in. The moisture would react with the refrigerant and the oil which is hydroscopic absorbs water and turns to acid and rots out the core.
All cars & trucks since at least the 70s turn on the a/c compressor when ever defrost mode is selected to remove moisture in the passenger compartment. a/c oil is not hydroscopic, the only fluid I'm aware of is brake fluid which will absorb water & thats why manufactures recommend changing it or flushing it.
P.S. The only thing that would prevent this is a low freon level. When this happens the low pressure cut off switch prevents the compressor from running to prevent system damage Jim
Definitely helps keeping all O-rings and seals (especially the compressor's shaft seal) ok and a good charge inside for a longer time. That's because the compressor lubricant oil, circulated with the refrigerant (and the best oil circulation rate is attained with a full system charge), keeps them from drying up and then letting the system's contents escape to the atmosphere. Let your compressor run a few minutes each week.
This, however, won't apply with a clutchless compressor: these compressors, with the engine on, are always turning and pumping something around the system. With these, you only have to care about not letting the car sit around too much without being turned on.