Do I have to flash the computer in my 2005 Cadillac Deville after replacing the transmission with a used unit

  • with the same model/part number transmission? no. – Ben Apr 1 '17 at 23:26

As Ben commented, if you use an identical part (same model and part number as the original one) then you should not need to reflash, as the expected settings will be different.

If, however you have used a different model/part then you will need to look at the guidance on whether it requires a reflash. Cadillac should have guidance on requirements, or sites like cardone.com and cargurus.com have useful info.

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